Custom Peptides
Cayman Chemical Lnsoprazole sulfon 10mg
A metabolite of lansoprazole; formed by metabolism of lansoprazole by CYP3A4
Cayman Chemical 14-TrIamcInolon acetonIde 10mg
A potential impurity found in commercial triamcinolone acetonide preparations
Cayman Chemical MethIothepInmaleate 10mg
A fluorescent membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which are engineered into target proteins
Cayman Chemical Curcuma Rhzoma Curcumnl 10mg
A sesquiterpene; active against methicillin-resistant S. aureus (MRSA) and P. aeruginosa; cytotoxic to CEM-SS lymphoblastic leukemia cells (IC50 = 11.9 UG/ml); decreases cell viability of AGS human gastric carcinoma cells (IC50 = 263.34 µM)
Cayman Chemical ZunsemetInIb 10mg
An MK2-biased p38α MAPK inhibitor; selectively inhibits p38α MAPK-dependent activation of MK2 over p38α MAPK-dependent activation of MK5 and ATF2 by 750- and 700-fold, respectively; greater than 350-fold selective for p38α MAPK over a panel of 193 other kinases at 5 µM; reduces LPS-induced increases in the levels of mRNA encoding Il-1β in isolated mouse BMMs at 10 µM; reduces body weight loss, neutrophilia, and the number of osteoclasts at trabecular and cortical bone surfaces in a model of NOMIDc using Nlrp3fl(D301N)/+;CreER mice; enhances decreases in tumor volume and increases in survival in an autochthonous KPC murine PDAC model when used in combination with FIRINOX
Cayman Chemical TubermycIn B 10mg
A bacterial metabolite; active against A. flavus, C. albicans, F. oxysporum, R. solani, and T. rubrum (MICs = 64, 8, 125, 32, and 4 UG/ml, respectively); prevents the development of foliar anthracnose lesions in C. orbiculare-infected cucumber plants
Cayman Chemical Selnkacetate 10mg
A synthetic derivative of the tetrapeptide tuftsin that contains a Pro-Gly-Pro sequence at the C-terminus; increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region at 1 μM; decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test; increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test; decreases apomorphine-induced verticalization in mice at 0.01 mg/kg; decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes at 100 μg/kg
Cayman Chemical 1MyrIstoyl2Oleoyl3PalmIt 10mg
A triacylglycerol; has been found in butterfat and the fat body of male B. hortorum bumblebees; has also been found as a minor triacylglycerol preserved in the subcutaneous fat of the 5,300-year-old Iceman mummy
Cayman Chemical GSK1904529A 10mg
A dual InsR and IGF-1R kinase inhibitor (IC50s = 25 and 27 nM, respectively, in a cell-free assay); selectively inhibits InsR and IGF-1R kinases over a panel of 45 serine/threonine and tyrosine kinases (IC50s = >1 µM for all); decreases proliferation of 13 cancer cell lines including multiple myeloma, sarcoma, colon, and breast cancer cells (IC50s = 35-189 nM) in a panel of 35 cell lines; reduces tumor growth in NIH3T3-LISN, COLO 205, HT-29, and BxPC3 mouse xenograft models at 30 mg/kg for 21 days
Cayman Chemical JWH 018 N 2hydroxypenty 10mg
A potential metabolite of JWH 018, detectable in serum and in urine
Cayman Chemical TuberostemonIn 10mg
An alkaloid; exhibits feeding deterrent and repellant activities against S. littoralis fifth instar larvae when applied to lettuce leaf disks at 0.01 and 0.1 UG/cm2, respectively; reduces the number of citric acid-induced coughs in guinea pigs at 100 mg/kg; decreases BALF neutrophil and macrophage infiltration and reduces peribronchial and perivascular inflammatory cell infiltration in a cigarette smoke-induced mouse model of acute lung inflammation from 1-10 mg/kg
Cayman Chemical OSILODROSTAT 10MG
An aldosterone synthase inhibitor; selective for human aldosterone synthase over rat aldosterone synthase (IC50 = 160 nM); inhibits increases in plasma aldosterone levels induced by angiotensin II or ACTH in rats (ED50s = 0.6 and 1.1 mg/kg, respectively); reduces mean arterial pressure and prolongs survival in rats expressing human renin and angiotensinogen, a double-transgenic model of angiotensin II-dependent hypertension, in a dose-dependent manner
Cayman Chemical BupIvacaIn-d9 10mg
An internal standard for the quantification of bupivacaine by GC- or LC-MS
Cayman Chemical Aceclofenac methyl ester 10mg
A potential impurity in commercial preparations of aceclofenac; has been used as a precursor in the synthesis of aceclofenac